Section Ii Production of Antibodies
ثبت نشده
چکیده
Antibodies are serum immunoglobulins with binding specificity for particular antigens. Although antibodies can be identified in the serum of individuals or patients that have been exposed to particular pathogens, the usual methods for eliciting antibodies involve immunization with purified or partially purified antigen preparations. Antigens used are most commonly proteins or peptides, but carbohydrates, nucleic acids, small organic molecules (haptens) conjugated to appropriate protein carriers, cells, and cell and tissue extracts can also be employed.
منابع مشابه
Production and Characterization of Murine Monoclonal Antibodies to Leishmania Gp63 Antigen
Background : Production of monoclonal antibodies to Leishmania antigens assists the identification and characterization of these organisms. Objective: Production of monoclonal antibodies against epitopes on the gp63. Methods: Two murine monoclonal antibodies to gp63 were produced and characterized. The reactions of both antibodies with soluble leishmanial antigens, purified gp63 and truncated r...
متن کاملINVESTIGATION ON ANTI-GLUTAMIC ACID DECARBOXYLASE ANTIBODIES IN TYPE I DIABE TES MELLITUS
Antibodies directed against the enzyme glutamic acid decarboxylase (GAD) are believed to be the main cause of destruction of pancreatic islet cells in type I (insulin dependent) diabetes mellitus. The enzyme was found both in the brain and pancreatic beta cells. Although similarities in identity of GAD in human and rat brain have been demonstrated, little is known about the interaction betw...
متن کاملThe role of platelet microparticles in the production of antibodies from B lymphocytes against HLA-DR antigen in vitro
Background: Platelets can activate B cells and stimulate them for the production of antibodies. Since platelet microparticles (PMPs) originate from platelets, they may have the same virtue. In the present study, the effect of PMPs was investigated on the production of human leukocyte antigen (HLA)-specific antibody from B cells in vitro. Materials and Methods: In this experimental study, HLA-D...
متن کاملProduction and Partial Characterization of Monoclonal Antibodies to Leishmania
Background: Monoclonal antibody technology allows identification of amastigote-specific antigen in human tissue biopsies and search for a suitable vaccine candidate, which may induce a long lasting immunity. Objectives: Production and partial characterization of seven monoclonal antibodies against Leishmania tropica promstigotes. Methods: Seven murine monoclonal antibodies of the IgG isotype we...
متن کاملFungal Infections of Respiratory Tract-Final Section
Histoplasma capsulatum var. capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Paracoccidioides brasiliensis, and Penicillium marneffei are endemic dimorphic fungi that may infect the respiratory tract. Sporothrix schenkeii, which manifests the typical thermal dimorphism of the endemic dimorphic organisms, does not seem to follow a geographically defined endemic pattern of distribution...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2003